Immune Modulation by Stem Cell Derived Exosomes in Critically Ill COVID-19
Status: Recruiting
Location: See location...
Intervention Type: Biological
Study Type: Observational
SUMMARY
Following whole blood stimulation with mesenchymal stem cell derived exosomes, immune phenotype, cytokine release and mRNA expression patterns from critically ill patients with COVID-19 will be determined.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 90
Healthy Volunteers: t
View:
• Critically ill COVID-19 patients with lung dysfunction
• COVID-19 WHO severity degree \>= 4, ARDS (WHO Definition 13 March 2020)
• Body weight \> 50 kg
• Informed consent
Locations
Other Locations
Germany
Ulm University Hospital, Clinic of Anesthesiology and Intensive Care Medicine
RECRUITING
Ulm
Contact Information
Primary
Manfred Weiss, MD
manfred.weiss@uniklinik-ulm.de
+49(0)731500
Backup
Marion Schneider, PhD
marion.schneider@uni-ulm.de
+49(0)731500
Time Frame
Start Date: 2021-12-22
Estimated Completion Date: 2026-12-31
Participants
Target number of participants: 40
Authors
Elisabeth M Schneider
Related Therapeutic Areas
Sponsors
Leads: University of Ulm